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| CHLOROPROCAINE HYDROCHLORIDE | ||
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PRODUCT IDENTIFICATION |
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| CAS NO. | 3858-89-7 |
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| EINECS NO. | ||
| FORMULA | C13H19ClN2O2HCl | |
| MOL WT. | 307.22 | |
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H.S. CODE |
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TOXICITY |
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| SYNONYMS | Nesacaine hydrochloride; | |
| 4-Amino-2-chloro-Benzoic acid, 2-(diethylamino)ethyl ester, hydrochloride; 2-(Diethylamino)ethyl 4-amino-2-chlorobenzoate hydrochloride; 2-Chloroprocaine hydrochloride; | ||
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CLASSIFICATION |
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GENERAL DESCRIPTION OF LOCAL ANESTHETIC |
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| Local anesthetic is a substance that causes loss of sensation only to the area to which it is applied without affecting consciousness. Most local anesthetics structures have amino-ester or an amino-amide group which are linked to hydrophilic (secondary or tertiary amine) and to hydrophobic group (aromatics) on the other sid. The ester can be hydrolysed in plasma by the enzyme pseudocholinesterase into para-aminobenzoic acid. Amide is stable for longer acting and more systemic distribution. Ester types include Procaine (Novocain), Chloroprocaine (Nesacaine), Cocaine, Tetracaine (Pontocaine), Benzocaine, Tetracaine. Amide types include Lidocaine (Xylocaine), Mepivacaine(Carbocaine), Prilocaine (Citanest), Bupivacaine (Marcaine), Etidocaine (Duranest). | ||
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PHYSICAL AND CHEMICAL PROPERTIES |
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| PHYSICAL STATE | White crystalline powder, odourless | |
| MELTING POINT |
176 C |
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| BOILING POINT | ||
| SPECIFIC GRAVITY | ||
| SOLUBILITY IN WATER |
Slightly soluble |
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| pH | 5 - 6.5 | |
| VAPOR DENSITY |
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| AUTOIGNITION |
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| NFPA RATINGS | ||
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REFRACTIVE INDEX |
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| FLASH POINT |
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| STABILITY |
Stable under ordinary conditions. |
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APPLICATIONS |
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| Chloroprocaine, in the form of a hydrochloride, is a local anaesthetic. | ||
| SALES SPECIFICATION | ||
| BP93/USP23 | ||
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APPEARANCE |
White crystalline powder | |
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ASSAY |
98.5% min |
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SULFATE |
0.2% max |
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| TRANSPORTATION | ||
| PACKING |
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| HAZARD CLASS | ||
| UN NO. | ||
| OTHER INFORMATION | ||
| Hazard Symbols: XN, Risk Phrases: 26/27/28, Safety Phrases: 22-36/37/39-45 | ||
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